产品
本公司产品仅供体外研究使用，不用于临床诊断
alpha-synuclein antibody
¥1900
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- alpha-synuclein antibody
- 货号
- FNab00345
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- synuclein, alpha (non A4 component of amyloid precursor)
- 别称
- Alpha synuclein antibody, NACP antibody, PARK1 antibody, PARK4 antibody, SNCA antibody
- UniProt ID
- P37840
- 分子量
- 15 kDa
验证实验
- 验证实验
- ELISA, IHC, WB, IF
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
验证图片
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00345(SNCA antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human brain using FNab00345(SNCA antibody) at dilution of 1:50
Immunofluorescent analysis of SH-SY5Y cells using FNab00345 (alpha-synuclein antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- 背景介绍
- Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
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