产品
本公司产品仅供体外研究使用，不用于临床诊断
AMBRA1 antibody
¥1750
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- AMBRA1 antibody
- 货号
- FNab00356
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- autophagy/beclin-1 regulator 1
- 别称
- AMBRA1 antibody, autophagy/beclin 1 regulator 1 antibody, FLJ20294 antibody, KIAA1736 antibody, WDR94 antibody
- UniProt ID
- Q9C0C7
- 分子量
- 140 kDa
验证实验
- 验证实验
- ELISA, IHC, WB
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00356(AMBRA1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab00356(AMBRA1 antibody) at dilution of 1:50
- 背景介绍
- WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. AMBRA1 (Activating molecule in BECN1-regulated autophagy protein 1), also known as WDR94 or KIAA1736, is a 1, 298 amino acid protein that contains three WD repeats. Localized to cytoplasmic vesicles, AMBRA1 functions to control protein turnover, cell proliferation and cell survival during neuronal development, thereby playing an important role in autophagy and the development of the nervous system. Multiple isoforms of AMBRA1 exist due to alternative spicing events.
抗体定制服务
抗体定制服务
