mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab00521(AQP4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab00521( AQP4 Antibody) at dilution of 1:200
背景介绍
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.