产品
本公司产品仅供体外研究使用，不用于临床诊断
ARNT2 antibody
¥1750
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- ARNT2 antibody
- 货号
- FNab00595
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- aryl-hydrocarbon receptor nuclear translocator 2
- 别称
- BHLHE1 antibody, KIAA0307 antibody
- UniProt ID
- Q9HBZ2
- 分子量
- 79 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00595(ARNT2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using FNab00595(ARNT2 antibody) at dilution of 1:100
- 背景介绍
- This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
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