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BAX antibody

别称:BCL2L4 antibody, Apoptosis regulator BAX antibody, BAX antibody
货号:FNab00809反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, WB, IHC, IF
克隆性:polyclonal亚型:IgG
¥1900
规格:
货期: 三个工作日+顺丰快递时长
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产品名称
BAX antibody
货号
FNab00809
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
BCL2-associated X protein
别称
BCL2L4 antibody, Apoptosis regulator BAX antibody, BAX antibody
UniProt ID
Q07812
分子量
21 kDa
验证实验
验证实验
ELISA, WB, IHC, IF
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200
验证图片
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00809(BAX antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab00809( BAX Antibody) at dilution of 1:50
背景介绍
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.