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Bestrophin-1 antibody

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说明书 MSDS

¥1750

规格：

货期：三个工作日+顺丰快递时长

产品名称: Bestrophin-1 antibody
货号: FNab00865
规格: 100μg
状态: liquid
纯化方法: Immunogen affinity purified
纯度: ≥95% as determined by SDS-PAGE
克隆性: polyclonal
亚型: IgG
存储: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

免疫原信息

验证实验

验证图片

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab00865(BEST1 antibody) at dilution of 1:1000

Immunohistochemistry of paraffin-embedded human liver injury using FNab00865( BEST1 Antibody) at dilution of 1:100

背景介绍: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.