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CD68 antibody

分类: 研究方向:
别称:CD68 antibody, CD68 molecule antibody, DKFZp686M18236 antibody, GP110 antibody, Macrosialin antibody, SCARD1 antibody
货号:FNab01491反应性:Human, Mouse
宿主:Rabbit验证实验:ELISA, IHC, WB
克隆性:polyclonal亚型:IgG
¥1750
规格:
货期: 三个工作日+顺丰快递时长
  • 产品介绍
产品名称
CD68 antibody
货号
FNab01491
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
CD68 molecule
别称
CD68 antibody, CD68 molecule antibody, DKFZp686M18236 antibody, GP110 antibody, Macrosialin antibody, SCARD1 antibody
UniProt ID
P34810
分子量
Refer to figures
验证实验
验证实验
ELISA, IHC, WB
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
Mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab01491 (CD68 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01491( CD68 Antibody) at dilution of 1:50
背景介绍
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.