产品
本公司产品仅供体外研究使用，不用于临床诊断
DPP4 antibody
¥2100
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- DPP4 antibody
- 货号
- FNab02520
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- dipeptidyl-peptidase 4
- 别称
- ADABP antibody, ADCP 2 antibody, ADCP2 antibody, CD26 antibody, dipeptidyl peptidase 4 antibody, Dipeptidyl peptidase IV antibody, DPP IV antibody, DPP4 antibody, DPPIV antibody, T cell activation antigen CD26 antibody, TP103 antibody
- UniProt ID
- P27487
- 分子量
- 110 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
验证图片
U-937 cells were subjected to SDS PAGE followed by western blot with FNab02520(DPP4 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab02520(DPP4 antibody) at dilution of 1:100
- 背景介绍
- Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix(ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
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