产品
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Endoglin/CD105 antibody
¥1750
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- Endoglin/CD105 antibody
- 货号
- FNab02761
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- endoglin
- 别称
- CD105 antibody, END antibody, Endoglin antibody, ENG antibody, FLJ41744 antibody, HHT1 antibody, ORW antibody, ORW1 antibody
- UniProt ID
- P17813
- 分子量
- 68-75 kDa, 170-180 kDa
验证实验
- 验证实验
- ELISA, WB, IP, IHC
- 建议稀释比例
- WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:2000-1:8000
验证图片
mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab02761(ENG antibody) at dilution of 1:300
IP Result of anti- CD105 (IP: FNab02761, 3ug; Detection: FNab02761 1:300) with mouse lung tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human pancreas using FNab02761(ENG antibody) at dilution of 1:4000
- 背景介绍
- This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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