产品
本公司产品仅供体外研究使用，不用于临床诊断
FADD antibody
¥1500
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- FADD antibody
- 货号
- FNab02941
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- Fas(TNFRSF6)-associated via death domain
- 别称
- FADD antibody, GIG3 antibody, MORT1 antibody, Protein FADD antibody
- UniProt ID
- Q13158
- 分子量
- 26 kDa
验证实验
- 验证实验
- ELISA, IHC, WB, IP
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200
验证图片
Hela cells were subjected to SDS PAGE followed by western blot with FNab02941(FADD Antibody) at dilution of 1:1000
IP Result of anti-FADD (IP:FNab02941, 4ug; Detection:FNab02941 1:300) with A549 cells lysate 3040ug.
Immunohistochemistry of paraffin-embedded human lung cancer using FNab02941(FADD antibody) at dilution of 1:50
- 背景介绍
- Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
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