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nNOS antibody

别称:bNOS antibody, Constitutive NOS antibody, IHPS1 antibody, N NOS antibody, NC NOS antibody, Neuronal NOS antibody, Nitric oxide synthase antibody, brain antibody, nNOS antibody, NOS antibody, NOS type I antibody, NOS1 antibody
货号:FNab05774反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, WB, IHC
克隆性:polyclonal亚型:IgG
¥1500
规格:
货期: 三个工作日+顺丰快递时长
  • 产品介绍
产品名称
nNOS antibody
货号
FNab05774
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
nitric oxide synthase 1(neuronal)
别称
bNOS antibody, Constitutive NOS antibody, IHPS1 antibody, N NOS antibody, NC NOS antibody, Neuronal NOS antibody, Nitric oxide synthase antibody, brain antibody, nNOS antibody, NOS antibody, NOS type I antibody, NOS1 antibody
UniProt ID
P29475
分子量
161kd
验证实验
验证实验
ELISA, WB, IHC
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05774(nNOS antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab05774(nNOS Antibody) at dilution of 1:50
背景介绍
nNOS belongs to the NOS family. NOS1 produces nitric oxide(NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NO is synthesized from L-arginine by nitric oxide synthases. NOS1 is a nitric oxide synthase which is highly expressed in skeletal muscle. Genetic variations in NOS1 gene are associated with susceptibility to infantile hypertrophic pyloric stenosis type 1(IHPS1).The antibody can recognize isoform 1,2,4,5 of NOS1.