产品

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PCNA antibody

别称:Proliferating cell nuclear antigen antibody, Cyclin antibody
货号:FNab06215反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, WB, IHC
克隆性:polyclonal亚型:IgG
¥750
规格:
货期: 三个工作日+顺丰快递时长
  • 产品介绍
产品名称
PCNA antibody
货号
FNab06215
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
proliferating cell nuclear antigen
别称
Proliferating cell nuclear antigen antibody, Cyclin antibody
UniProt ID
P12004
分子量
38 kDa
验证实验
验证实验
ELISA, WB, IHC
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
A431 cells were subjected to SDS PAGE followed by western blot with FNab06215(PCNA antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach cancer using FNab06215(PCNA antibody) at dilution of 1:50
背景介绍
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.