产品
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PER2 antibody
¥2100
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- PER2 antibody
- 货号
- FNab06312
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- period homolog 2
- 别称
- FASPS antibody, hPER2 antibody, KIAA0347 antibody, PER2 antibody, period homolog 2 antibody
- UniProt ID
- O15055
- 分子量
- 136 kDa
验证实验
- 验证实验
- ELISA, WB, IP
- 建议稀释比例
- WB: 1:500-1:2000; IP: 1:200-1:1000
验证图片
BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab06312(PER2 antibody) at dilution of 1:600
IP Result of anti-PER2 (IP:FNab06312, 3ug; Detection:FNab06312 1:300) with HEK-293 cells lysate 1000ug.
- 背景介绍
- PER2, also named as KIAA0347, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. PER2 is a negative element in the circadian transcriptional loop. PER2 influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. It negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS) which is characterized by very early sleep onset and offset.
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