产品
本公司产品仅供体外研究使用,不用于临床诊断
- 产品介绍
- 相关文献
- 产品名称
- Vinculin antibody
- 货号
- FNab09799
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- vinculin
- 别称
- CMD1W antibody, Metavinculin antibody, MVCL antibody, VCL antibody, Vinculin antibody
- UniProt ID
- P18206
- 分子量
- 124 kDa
验证实验
- 验证实验
- ELISA, IHC, WB
- 建议稀释比例
- WB: 1:500-1:2000; IHC: 1:50-1:200
验证图片
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09799(Vinculin Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using FNab09799( Vinculin Antibody) at dilution of 1:100
- 背景介绍
- Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
IF: 4.088
- 期刊名:
- Experimental Biology and Medicine
- 作者:
- Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, China
- 发布日期:
- 2023-06-16
- 引用产品: