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本公司产品仅供体外研究使用,不用于临床诊断
VEGF antibody
- 产品介绍
- 相关文献
- 产品名称
- VEGF antibody
- 货号
- FNab09933
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- protein A+G purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- monoclonal
- 亚型
- IgG2b
- Clone ID
- 5H5
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- vascular endothelial growth factor A
- 别称
- L VEGFA antibody, MVCD1 antibody, Vascular permeability factor antibody, VEGF antibody, VEGF A antibody, VEGFA antibody, VPF antibody
- UniProt ID
- P15692
- 分子量
- 45 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:1000-1:4000; IHC: 1:50-1:500
验证图片
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab09933 (VEGF antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using FNab09933 (VEGF antibody) at dilution of 1:200
- 背景介绍
- VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010). This antibody can recognize all the isoforms of VEFGA.
IF: 0.894
- 期刊名:
- Turkish Journal of Trauma and Emergency Surgery
- 发布日期:
- 2022-09-16
- 引用产品:
- 期刊名:
- Indonesian Journal of Pathology
- 发布日期:
- 2022-01-21
- 引用产品:
- 期刊名:
- Indonesian Journal of Pathology
- 发布日期:
- 2022-06-03
- 引用产品:
- 期刊名:
- SSRN
- 发布日期:
- 2022-08-26
- 引用产品: