产品
本公司产品仅供体外研究使用，不用于临床诊断
PKC gamma antibody
¥1500
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- PKC gamma antibody
- 货号
- FNab10007
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- protein kinase C, gamma
- 别称
- PKC gamma antibody, PKCC antibody, PKCG antibody, PRKCG antibody, Protein kinase C gamma type antibody, protein kinase C antibody, gamma antibody, SCA14 antibody
- UniProt ID
- P63318
- 分子量
- 78 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:500-1:2000; IHC: 1:100-1:500
验证图片
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab10007(PRKCG antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain tissue slide using FNab10007(PRKCG Antibody) at dilution of 1:200
- 背景介绍
- Protein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14(SCA14), an autosomal dominant neurodegenerative disease.
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