产品

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Endoglin/CD105 antibody

别称:CD105 antibody, END antibody, Endoglin antibody, ENG antibody, FLJ41744 antibody, HHT1 antibody, ORW antibody, ORW1 antibody
货号:FNab10035反应性:Human
宿主:Rabbit验证实验:ELISA, WB
克隆性:polyclonal亚型:IgG
¥1500
规格:
货期: 三个工作日+顺丰&京东快递时长
  • 产品介绍
产品名称
Endoglin/CD105 antibody
货号
FNab10035
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
endoglin
别称
CD105 antibody, END antibody, Endoglin antibody, ENG antibody, FLJ41744 antibody, HHT1 antibody, ORW antibody, ORW1 antibody
UniProt ID
P17813
分子量
50 kDa, 67 kDa
验证实验
验证实验
ELISA, WB
建议稀释比例
WB: 1:200-1:2000
验证图片
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab10035(ENG antibody) at dilution of 1:1000
背景介绍
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.