产品
本公司产品仅供体外研究使用，不用于临床诊断
SMARCA4 antibody
¥1500
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- SMARCA4 antibody
- 货号
- FNab10044
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- 别称
- ATP dependent helicase SMARCA4 antibody, BAF190 antibody, BAF190A antibody, BRG1 antibody, BRG1 associated factor 190A antibody, FLJ39786 antibody, hSNF2b antibody, Protein brahma homolog 1 antibody, Protein BRG 1 antibody, SMARCA4 antibody, SNF2 antibody, SNF2 BETA antibody, SNF2B antibody, SNF2L4 antibody, SNF2LB antibody, SWI2 antibody, Transcription activator BRG1 antibody
- UniProt ID
- P51532
- 分子量
- 185 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
HeLa cells were subjected to SDS PAGE followed by western blot with FNab10044(SMARCA4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab10044(SMARCA4 antibody) at dilution of 1:100
- 背景介绍
- SMARCA4, also named as BAF190A, BRG1, SNF2B and SNF2L4, belongs to the SNF2/RAD54 helicase family. SMARCA4 is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. It is a component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. It is also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor(VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
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