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CD14 antibody

分类：

研究方向：

别称：	CD14 antibody, CD14 molecule antibody
货号：	FNab10077	反应性：	Human
宿主：	Rabbit	验证实验：	ELISA, IHC
克隆性：	polyclonal	亚型：	IgG

说明书

¥1500

规格：

货期：三个工作日+顺丰&京东快递时长

产品名称: CD14 antibody
货号: FNab10077
规格: 100μg
状态: liquid
纯化方法: Immunogen affinity purified
纯度: ≥95% as determined by SDS-PAGE
克隆性: polyclonal
亚型: IgG
存储: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

免疫原信息

验证实验

验证图片

Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab10077(CD14 Antibody) at dilution of 1:200

背景介绍: Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211).