产品

本公司产品仅供体外研究使用,不用于临床诊断

PTCH1 antibody

别称:HPE7 antibody, NBCCS antibody, Patched antibody, patched homolog 1 antibody, Patched1 antibody, Protein patched homolog 1 antibody, PTC antibody, PTC1 antibody, PTCH antibody, PTCH1 antibody, PTCH11 antibody
货号:FNab10084反应性:Human, Rat
宿主:Rabbit验证实验:ELISA, IHC
克隆性:polyclonal亚型:IgG
¥1500
规格:
货期: 三个工作日+顺丰&京东快递时长
  • 产品介绍
产品名称
PTCH1 antibody
货号
FNab10084
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
patched homolog 1
别称
HPE7 antibody, NBCCS antibody, Patched antibody, patched homolog 1 antibody, Patched1 antibody, Protein patched homolog 1 antibody, PTC antibody, PTC1 antibody, PTCH antibody, PTCH1 antibody, PTCH11 antibody
UniProt ID
Q13635
分子量
161 kDa
验证实验
验证实验
ELISA, IHC
建议稀释比例
IHC: 1:20-1:200
验证图片
Immunohistochemistry of paraffin-embedded human colon cancer using FNab10084(PTCH1 antibody) at dilution of 1:50
背景介绍
Acts as a receptor for sonic hedgehog(SHH), indian hedgehog(IHH) and desert hedgehog(DHH). Associates with the smoothened protein(SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.