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EIF5A antibody

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说明书

¥1500

规格：

货期：三个工作日+顺丰&京东快递时长

产品名称: EIF5A antibody
货号: FNab10466
规格: 100μg
状态: liquid
纯化方法: Immunogen affinity purified
纯度: ≥95% as determined by SDS-PAGE
克隆性: polyclonal
亚型: IgG
存储: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

免疫原信息

验证实验

验证图片

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab10466(EIF5A antibody) at dilution of 1:1000

Immunohistochemistry of paraffin-embedded rat lung using FNab10466(EIF5A antibody) at dilution of 1:100

背景介绍: mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.