趋化因子(chemokines)也称趋化激素、趋化素或化学激素,是一类分子量仅8~10 kD的小分子细胞因子家族,因其对白细胞等具有定向趋化作用而得名。趋化因子的结构特征是具有4个保守的半胱氨酸残基位点,从而保证其稳定的三级结构。根据其 N 末端四个半胱氨酸序列，它们通常被分为 CXC、CC、CX3C和C四个亚家族。趋化因子通过结合G蛋白偶连跨膜受体进行信号转导。趋化因子是一种多功能介质，主要负责将白细胞募集到炎症组织。趋化因子信号网络由约50个分泌配体和20个GPCR组成。研究表明，这一复杂的系统参与了多种生理过程，包括在免疫反应中调节细胞迁移。
趋化因子
FineTest®ELISA试剂盒产品优势
1、拥有蛋白和抗体研发生产的能力，原料大部分自产，质量可控；
2、拥有自己的细胞库，血液组织样品库，为检测提供丰富的样品；
3、拥有GMP车间，保证生产环境的洁净度，提高产品的可靠性；
4、独特的信号放大技术，能灵活调整试剂盒的灵敏度，并有能力提高客户样品检出率；
5、使用高精密机器生产，和严格的质控，保证批次差小于5%，并进行大量样品检测，确保质量可靠；
6、使用独特的稳定技术，让试剂盒可以在室温放置一个月也不会失活，方便运输和使用。
相关产品
CC 趋化因子，是一类具有低分子量 (8-15 kDa) 的可溶性蛋白质，具有 N 末端 CC 结构域，最初被确定为炎症过程的介质和白细胞运输的调节剂。所有趋化因子都具有相同的整体结构：至少三个 β 折叠片、C 末端结构域中的一个 α 螺旋以及连接保守半胱氨酸残基的二硫键。根据前两个 N 末端半胱氨酸残基在其氨基酸序列中的排列，趋化因子可以分为四个家族：CXC（或 α）家族、CC（或 β）家族、CX3C（或 δ）家族，以及 C（或γ）家族。大多数趋化因子通过激活 G 蛋白偶联七次跨膜受体 (GPCR) 发挥其生物学作用。趋化因子是一类可溶性细胞因子，可作为化学引诱剂来引导细胞（尤其是免疫细胞）的迁移，也参与细胞增殖、分化和存活，与多种人类疾病相关，包括慢性炎症、免疫功能障碍、癌症和转移等
|
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
目录价 |
|
Human |
EH4867 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Mouse |
EM0026 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Rat |
ER0810 |
37.5pg/ml |
62.5-4000pg/ml |
¥2,480 |
|
|
Human |
EH0121 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Rat |
ER0198 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Mouse |
EM0996 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Mouse |
EM0027 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Human |
EH0056 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0057 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0058 |
11.719pg/ml |
19.531-1250pg/ml |
¥2,480 |
|
|
Human |
EH0059 |
46.875pg/ml |
78.125-5000pg/ml |
¥2,480 |
|
|
Human |
EH0060 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Human |
EH0061 |
46.875pg/ml |
78.125-5000pg/ml |
¥2,480 |
|
|
Human |
EH0002 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Mouse |
EM1211 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Rat |
ER1156 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0222 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Mouse |
EM0135 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Rat |
ER0047 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0231 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Mouse |
EM1210 |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
|
|
Rat |
ER0050 |
46.875pg/ml |
78.125-5000pg/ml |
¥2,480 |
|
|
Rat |
ER1145 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0223 |
37.5pg/ml |
62.5-4000pg/ml |
¥2,480 |
|
|
Mouse |
EM0137 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0063 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0064 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0065 |
37.5pg/ml |
62.5-4000pg/ml |
¥2,480 |
|
|
Human |
EH3361 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Human |
EH0066 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0675 |
0.188ng/ml |
0.313-20ng/ml |
¥2,480 |
|
|
Mouse |
EM1932 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Human |
EH0230 |
14.063pg/ml |
23.438-1500pg/ml |
¥2,480 |
|
|
Rat |
ER0049 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Mouse |
EM1208 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0067 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Rat |
ER1153 |
0.938pg/ml |
1.563-100pg/ml |
¥2,480 |
|
|
Mouse |
EM1209 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Mouse |
EM1474 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0068 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Mouse |
EM1204 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Rat |
ER0048 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0069 |
3.75pg/ml |
6.25-400pg/ml |
¥2,480 |
|
|
Mouse |
EM1203 |
3.75pg/ml |
6.25-400pg/ml |
¥2,480 |
|
|
Mouse |
EM1931 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0005 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
CXC亚家族 (α-chemokines) 是多效的细胞因子，其特征是四个高度保守的半胱氨酸氨基酸残基中，两个半胱氨酸残基 (C)被一个非半胱氨酸残基 (X) 间隔开。CXC亚家族因具有促进各种白细胞运输和调节血管生成和血管重塑的能力而广为人知。根据CXC趋化因子中 ELR基序 (Glu-Leu-Arg 序列) 的存在与否，被认为是有效的血管生成启动子或抑制剂。
|
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
目录价 |
|
Rat |
ER1014 |
3.75pg/ml |
6.25-400pg/ml |
¥2,480 |
|
|
Mouse |
EM0003 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0102 |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
|
|
Rat |
ER0029 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Mouse |
EM0004 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Human |
EH0006 |
37.5pg/ml |
62.5-4000pg/ml |
¥2,480 |
|
|
Human |
EH0103 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH1843 |
0.094ng/ml |
0.156-10ng/ml |
¥2,480 |
|
|
Mouse |
EM0878 |
0.094ng/ml |
0.156-10ng/ml |
¥2,480 |
|
|
Rat |
ER0776 |
56.25pg/ml |
93.75-6000pg/ml |
¥2,480 |
|
|
Human |
EH0105 |
0.094ng/ml |
0.156-10ng/ml |
¥2,480 |
|
|
Mouse |
EM0005 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Rat |
ER0882 |
0.094ng/ml |
0.156-10ng/ml |
¥2,480 |
|
|
Rat |
ER1015 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Mouse |
EM1090 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH3178 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH3179 |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
|
|
Mouse |
EM1091 |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
|
|
Rat |
ER1016 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0106 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Mouse |
EM1004 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Rat |
ER0922 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0107 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Mouse |
EM2021 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0007 |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
|
|
Human |
EH0008 |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
|
|
Mouse |
EM0967 |
28.125pg/ml |
46.875-3000pg/ml |
¥2,480 |
|
|
Rat |
ER1157 |
0.094ng/ml |
0.156-10ng/ml |
¥2,480 |
|
|
Rat |
ER0024 |
0.094ng/ml |
0.156-10ng/ml |
¥2,480 |
|
|
Human |
EH0141 |
75pg/ml |
125-8000pg/ml |
¥2,480 |
|
|
Mouse |
EM0008 |
0.234ng/ml |
0.391-25ng/ml |
¥2,480 |
引用文献
European Journal of Cancer IF: 10.0020
Lenvatinib, toripalimab plus hepatic arterial infusion chemotherapy in patients with high-risk advanced hepatocellular carcinoma: A biomolecular exploratory, phase II trial- 货号
- 产品名称
- EH0675
- Human CCL28(C-C motif chemokine 28) ELISA Kit
- EH0044
- Human BTC(Betacellulin) ELISA Kit