2019新型冠状病毒，又叫2019-nCoV，SARS-CoV-2，SARS-CoV2。新型冠状病毒和SARS冠状病毒(SARS-CoV)是同一类，但不是同一种。基因为单链RNA。新冠病毒是由4种主要的结构蛋白：刺突表面糖蛋白(S)、小包膜蛋白(E)、基质蛋白(M)、核衣壳蛋白(N)；
Spike蛋白(含S1和S2两个亚基)是冠状病毒最重要的致病蛋白，其和人体细胞膜上的跨膜受体蛋白质ACE2结合，从而帮助自己进入细胞内部。S蛋白很大，根据空间结构可以分为S1和S2两个部分，S1包含受体结合区域(receptor binding domain，RBD)，负责识别细胞的受体。S2含有膜融合过程所需的基本元件。目前研究的都是S1-RBD蛋白，是抗体药物的靶点。
核酸和蛋白质外壳就是病毒最重要的组成部分，核酸负责繁殖后代的遗传物质，蛋白质外壳负责保护遗传物质。冠状病毒因为其外壳像一顶皇冠而得名，研究发现这些皇冠一样的刺突就是刺突糖蛋白(Spike Glycoprotein，以下简称 S 蛋白)，是结合人体细胞上相应受体的罪魁祸首。因此它是感染后中和抗体(nAbs)的主要目标，也是治疗和疫苗设计的重点。
菲恩生物开发相关产品：
ELISA试剂盒：
|
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
|
Human |
EH5032 |
Human anti- SARS-CoV-2 (COVID) Spike RBD Alpha B.1.1.7 Variant (UK Variant) IgA ELISA Kit |
0.469ng/ml |
0.781-50ng/ml |
|
Human |
EH5030 |
Human anti- SARS-CoV-2 (COVID) Spike RBD Alpha B.1.1.7 Variant (UK Variant) IgG ELISA Kit |
0.938ng/ml |
1.563-100ng/ml |
|
Human |
EH5031 |
Human anti- SARS-CoV-2 (COVID) Spike RBD Alpha B.1.1.7 Variant (UK Variant) IgM ELISA Kit |
0.469ng/ml |
0.781-50ng/ml |
|
Human |
EH4950 |
0.234ng/ml |
0.391-25ng/ml |
|
|
Human |
EH4943 |
2.344ng/ml |
3.906-250ng/ml |
|
|
Human |
EH4944 |
0.469ng/ml |
0.781-50ng/ml |
|
|
Human |
EH4956 |
0.234ng/ml |
0.391-25ng/ml |
|
|
Human |
EH4951 |
0.469ng/ml |
0.781-50ng/ml |
|
|
Human |
EH4397 |
2.344ng/ml |
3.906-250ng/ml |
|
|
Human |
EH4940 |
0.469ng/ml |
0.781-50ng/ml |
|
|
Human |
EH4981 |
2.344ng/ml |
3.906-250ng/ml |
|
|
Human |
EH5001 |
Human anti-SARS-CoV2 (S-RBD) (Omicron,B.1.1.529) IgM ELISA Kit |
0.938ng/ml |
1.563-100ng/ml |
|
Human |
EH5002 |
Human anti-SARS-CoV2 (S-RBD) (Omicron,B.1.1.529) IgA ELISA Kit |
0.938ng/ml |
1.563-100ng/ml |
|
Human |
EH5009 |
0.938ng/ml |
1.563-100ng/ml |
|
|
Human |
EH5007 |
2.34ng/ml |
3.9-250ng/ml |
|
|
Human |
EH5008 |
0.938ng/ml |
1.563-100ng/ml |
|
|
Human |
EH4971 |
Human anti-SARS-CoV2 (S-RBD) (Omicron,B.1.1.529) IgG ELISA Kit |
2.34ng/ml |
3.9-250ng/ml |
|
Human |
EH4395 |
Qualitative |
Qualitative |
|
|
Human |
EH4396 |
Qualitative |
Qualitative |
|
|
Human |
EH4946 |
Qualitative |
Qualitative |
|
|
Human |
EH4948 |
Qualitative |
Qualitative |
|
|
Human |
EH4941 |
Qualitative |
Qualitative |
|
|
Human |
EH4942 |
Qualitative |
Qualitative |
|
|
Mouse |
EM1959 |
2.34ng/ml |
3.9-250ng/ml |
|
|
Mouse |
EM1906 |
0.094ng/ml |
0.156-10ng/ml |
|
|
Mouse |
EM1907 |
0.938ng/ml |
1.563-100ng/ml |
|
|
Mouse |
EM1908 |
0.469ng/ml |
0.781-50ng/ml |
|
|
Mouse |
EM2059 |
0.938ng/ml |
1.563-100ng/ml |
|
|
Mouse |
EM2082 |
0.094ng/ml |
0.156-10ng/ml |
|
|
Mouse |
EM1970 |
Mouse Anti SARS-CoV-2 (COVID) Spike RBD Alpha B.1.1.7 Variant (UK Variant) IgG ELISA Kit |
0.938ng/ml |
1.563-100ng/ml |
|
Mouse |
EM1971 |
Mouse Anti SARS-CoV-2 (COVID) Spike RBD Alpha B.1.1.7 Variant ( UK Variant) IgM ELISA Kit |
0.469ng/ml |
0.781-50ng/ml |
|
Mouse |
EM2122 |
1.875ng/ml |
3.125-200ng/ml |
|
|
Mouse |
EM2121 |
0.938ng/ml |
1.563-100ng/ml |
|
|
Mouse |
EM2037 |
Mouse anti-SARS-CoV2 (S-RBD) (Omicron,B.1.1.529) IgG ELISA Kit |
0.938ng/ml |
1.563-100ng/ml |
|
Mouse |
EM1961 |
Qualitative |
Qualitative |
|
|
Mouse |
EM1962 |
Qualitative |
Qualitative |
|
|
Hamster |
EHA0024 |
0.938ng/ml |
1.563-100ng/ml |
|
|
Hamster |
EHA0026 |
0.938ng/ml |
1.563-100ng/ml |
|
|
Hamster |
EHA0025 |
0.938ng/ml |
1.563-100ng/ml |
|
|
Pig |
EP0384 |
1.875ng/ml |
3.125-200ng/ml |
|
|
Pig |
EP0379 |
Pig anti-SARS-CoV2 (S-RBD) (Delta B.1.617.2) antibody ELISA Kit |
1.875ng/ml |
3.125-200ng/ml |
|
Rat |
ER2061 |
Rat anti- SARS-CoV-2 (COVID) Spike RBD Alpha B.1.1.7 Variant (UK Variant) IgG ELISA Kit |
0.938ng/ml |
1.56-100ng/ml |
|
Rat |
ER2062 |
Rat anti- SARS-CoV-2 (COVID) Spike RBD Alpha B.1.1.7 Variant (UK Variant) IgM ELISA Kit |
0.469ng/ml |
0.781-50ng/ml |
|
COVID-19 |
AQ-U3128 |
390fg/ml |
0.78-50pg/ml |
|
|
Universal |
EU3125 |
Qualitative |
Qualitative |
蛋白：
|
货号 |
产品名称 |
表达宿主 |
表达区间 |
标签 |
|
P3302 |
HEK293 cells |
16-685 |
C-terminal His Tag |
|
|
P3018 |
HEK293 cells |
16-1213 |
C-terminal His-Avi Tag |
|
|
P3006 |
HEK293 cells |
315-535 |
C-terminal His Tag |
|
|
P8614 |
Recombinant SARS-CoV-2 Spike Glycoprotein RBD [Omicron B.1.1.529] |
CHO cells |
319-541 |
C-terminal Fc Tag |
|
P8823 |
HEK293 cells |
16-685 |
C-terminal His Tag |
|
|
P8790 |
HEK293 cells |
686-1213 |
C-terminal Fc Tag |
|
|
P8947 |
HEK293 cells |
16-121 |
C-terminal His Tag |
|
|
P3003 |
E.Coli |
1-419 |
N-terminal His Tag |
|
|
P2908 |
E.Coli |
1-419 |
N-terminal His Tag |
|
|
P3123 |
E.Coli |
1-419 |
N-terminal His Tag |
|
|
P1023 |
E.Coli |
1-182 |
N-terminal His Tag |
|
|
P1024 |
E.Coli |
227-419 |
N-terminal His Tag |
抗体：
|
货号 |
产品名称 |
宿主 |
克隆性 |
适用种属 |
验证应用 |
|
FNab10307 |
Mouse |
monoclonal |
Human |
Colloidal Gold-Based, ELISA, IHC, WB |
|
|
FNab10306 |
Mouse |
monoclonal |
Human |
Colloidal Gold-Based, ELISA, IHC, WB |
|
|
FNab10309 |
Mouse |
monoclonal |
2019 nCOV |
ELISA, WB, Colloidal Gold-Based |
|
|
FNab10600 |
Rabbit |
monoclonal |
2019 nCOV |
ELISA, WB, Colloidal Gold-Based |
|
|
FNab10601 |
Rabbit |
monoclonal |
2019 nCOV |
ELISA, WB, Colloidal Gold-Based |
|
|
FNab10400 |
Human |
monoclonal |
2019 nCOV S protein |
ELISA, WB |
