抗体药物ELISA试剂盒

治疗性单克隆抗体和抗药物抗体

菲恩生物ELISA 试剂盒用于检测和定量治疗性单克隆抗体，如贝伐珠单抗和生物仿制药（包括利妥昔单抗和阿达木单抗），包括抗药物抗体(ADAs)的免疫原性检测。

产品优势：

高特异性 高灵敏度 高精度
与非靶标人血清蛋白或免疫球蛋白无交叉反应； 灵敏度高，检测范围广； 板内和批间差小；

单克隆抗体是外源性蛋白质，虽然它们中的大多数已被人源化重链修饰，但是Fab区仍然具有免疫原性的，在长期注射过程中经常发生过敏和免疫反应。菲恩生物研发了相关ELISA试剂盒，以帮助科研人员确定药物治疗过程中的新陈代谢。

货号 产品名称
EU2594 Bevacizumab
EH5110 Anti-Bevacizumab
EH4515 Denosumab
EH5125 Anti-Denosumab
EH5127 Anti-Denosumab
EH5106 Adalimumab
EH5107 Anti-Adalimumab
EH5126 Anti-Adalimumab
EH5122 Golimumab
EH5109 anti-Golimumab
EU2668 Anti-Panitumumab
EH5355 Anti-Natalizumab
EH5322 Anti-Vedolizumab
EH5327 Anti-Isatuximab
EH5321 Anti-Ustekinumab
EU3589 Infliximab
EU3590 Anti-Infliximab
EH5144 Trastuzumab
EH5252 Anti-trastuzumab
EH5145 Pertuzumab
EH5146 Anti-Pertuzumab
EH5134 Aflibercept
EH5135 Anti-Aflibercept
EH5289 Anti-Donanemab
EH5315 Tocilizumab
EU2667 Panitumumab
EH5310 Ramucirumab
EH5290 dupilumab
EH5291 Anti-dupilumab
EH5131 Romosozumab
EH5292 Anti-Romosozumab
EU2639 Faricimab
EH5293 Anti-Faricimab
EU2636 Enfortumab
EH5294 Anti-Enfortumab
EU2616 Rituximab
EH5295 Anti-Rituximab
EH5113 anti-hCD28 mAb
EH5114 anti-hCD3ε mAb
EH5241 Anti-Semaglutide
EH5142 Anti-hVEGF
EH5320 Ustekinumab
EU2672 Trastuzumab Emtansine
EU2693 Pertuzumab NAb
EU2712 Pembrolizumab NAb
EU2647 Pembrolizumab
EU2648 Omalizumab
EU2703 Ocrelizumab
EH5349-CM Nivolumab
EH5349 Nivolumab
EU3126 LPS
EM2186 LPS
EU2683 Levilimab
EU2694 Guselkumab
EU2710 Glofitamab
EU2701 Daratumumab
EU2704 Burosumab
EU2708 Benralizumab NAb
EU2707 Benralizumab ADA
EU2713 Atezolizumab NAb
EU2702 Atezolizumab
EH5252-CM Anti-trastuzumab
EH5357 Anti-T-DXd
EU2671 Anti-Pembrolizumab
EU6141 Anti-Ocrelizumab
EH5348 Anti-Nivolumab
EU2695 Anti-Guselkumab
EU6013 Anti-Daratumumab
EU2705 Anti-burosumab
EU2709 Anti-Atezolizumab

聚乙二醇抗体

菲恩生物开发的PEG(聚乙二醇)抗体ELISA试剂盒系列对PEG修饰的蛋白或药物所诱导的免疫反应进 行研究，该试剂盒采用间接法。对人、猴、大鼠和家兔产生的抗PEG IgM 和 IgG 抗体进行了定量检测。菲恩生物相关ELISA试剂盒如下：

货号 产品名称 靶点 灵敏度 检测范围
EH5111 Human anti-PEG(Polyethylene glycol) IgG ELISA Kit PEG 0.375ng/ml 0.625-40ng/ml
EH5112 Human anti-PEG(Polyethylene glycol) IgM ELISA Kit PEG 0.188ng/ml 0.313-20ng/ml
EM2149 Mouse anti-PEG(Polyethylene glycol) IgG ELISA Kit PEG 0.469ng/ml 0.781-50ng/ml
EM2150 Mouse anti-PEG(Polyethylene glycol) IgM ELISA Kit PEG 0.188ng/ml 0.313-20ng/ml
ER2094 Rat anti-PEG(Polyethylene glycol) IgG ELISA Kit PEG 0.75ng/ml 1.25-80ng/ml
ER2095 Rat anti-PEG(Polyethylene glycol) IgM ELISA Kit PEG 0.094ng/ml 0.156-10ng/ml
ERB0231 Rabbit anti-PEG(Polyethylene glycol) IgG ELISA Kit PEG 0.375ng/ml 0.625-40ng/ml
ERB0232 Rabbit anti-PEG(Polyethylene glycol) IgM ELISA Kit PEG 0.094ng/ml 0.156-10ng/ml
EMK0221 Monkey anti-PEG(Polyethylene glycol) IgG ELISA Kit PEG 0.375ng/ml 0.625-40ng/ml
EMK0222 Monkey anti-PEG(Polyethylene glycol) IgM ELISA Kit PEG 0.188ng/ml 0.313-20ng/ml

宿主细胞残留蛋白

HCPs是来自细胞培养过程中细胞的结构蛋白和分泌蛋白。有研究表明HCPs会刺激人体免疫系统，引起过敏反应或其他不良反应。此外，HCPs还可能引发机体对蛋白药物产生抗体，影响药物的治疗效果。在抗体药物生产过程中，必须严格控制HCPs残留。菲恩生物相关ELISA试剂盒如下：

货号 产品名称 灵敏度 检测范围
EU2662 Protein A ELISA Kit 20pg/ml 78.125-5000pg/ml
EU2614 CHO HCPs (Chinese Hamster Ovary host cell proteins) ELISA Kit 0.188ng/ml 0.313-20ng/ml
EU2624 E.coli HCPs(E.coli host cell proteins) ELISA Kit 1.875ng/ml 3.125-200ng/ml
EU3126 LPS(Lipopolysaccharides) ELISA Kit 0.188ug/ml 0.313-20ug/ml
EU3133 PEA(Pseudomonas Exotoxin A) ELISA Kit 18.75pg/ml 31.25-2000pg/ml
EU3135 OVA(Ovalbumin) ELISA Kit 0.469ng/ml 0.781-50ng/ml
EH4435-CM HEK 293 HCPs(HEK 293 host cell proteins) ELISA Kit 46.875ng/ml 78.125-5000ng/ml
EB0148 Bovine serum albumin(BSA) ELISA Kit 0.094ug/ml 0.156-10ug/ml
EMK0179 VERO HCPs(VERO host cell proteins) ELISA Kit 0.188ng/ml 0.313-20ng/ml
EP0253 Porcine TRY (Trypsin) ELISA Kit 0.938ng/ml 1.563-100ng/ml
EH4983 Human anti-cell free DNA ELISA Kit 0.938ng/ml 1.563-100ng/ml
EH4955 Human DS-DNA-IgG(double stranded DNA-Immunoglobulin G) ELISA Kit Qualitative Qualitative
EU2607 FLAG-Tag (DYKDDDDK-Tag Protein ) ELISA Kit 9.375ng/ml 15.625-1000ng/ml

产品对比