产品
本公司产品仅供体外研究使用，不用于临床诊断
ATG4B antibody
¥1750
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- ATG4B antibody
- 货号
- FNab00674
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- ATG4 autophagy related 4 homolog B
- 别称
- APG4B antibody, AUTL1 antibody, KIAA0943 antibody
- UniProt ID
- Q9Y4P1
- 分子量
- 44 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IP
- 建议稀释比例
- WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200
验证图片
human brain tissue were subjected to SDS PAGE followed by western blot with FNab00674(ATG4B antibody) at dilution of 1:800
IP Result of anti-ATG4B (IP:FNab00674, 4ug; Detection:FNab00674 1:500) with mouse skeletal muscle tissue lysate 3600ug.
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab00674(ATG4B antibody) at dilution of 1:50
- 背景介绍
- Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
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