产品

本公司产品仅供体外研究使用,不用于临床诊断

ULK1 antibody

别称:ATG1 antibody, FLJ38455 antibody, FLJ46475 antibody, KIAA0722 antibody, ULK1 antibody, Unc 51 like kinase 1 antibody, UNC51 antibody, Unc51.1 antibody
货号:FNab09251反应性:Human, Rat
宿主:Rabbit验证实验:ELISA, WB,IHC
克隆性:polyclonal亚型:IgG
¥2100
规格:
货期: 三个工作日+顺丰&京东快递时长
  • 产品介绍
产品名称
ULK1 antibody
货号
FNab09251
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
unc-51-like kinase 1(C. elegans)
别称
ATG1 antibody, FLJ38455 antibody, FLJ46475 antibody, KIAA0722 antibody, ULK1 antibody, Unc 51 like kinase 1 antibody, UNC51 antibody, Unc51.1 antibody
UniProt ID
O75385
分子量
150 kDa
验证实验
验证实验
ELISA, WB,IHC
建议稀释比例
WB: 1:200-1:1000; IHC: 1:50-1:500
验证图片
rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab09251(ULK1 Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab09251(ULK1 Antibody) at dilution of 1:200?
背景介绍
ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).