产品
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AEG-1/MTDH-Specific antibody
¥1750
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- AEG-1/MTDH-Specific antibody
- 货号
- FNab00189
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- metadherin
- 别称
- 3D3 antibody, 3D3/LYRIC antibody, AEG 1 antibody, AEG1 antibody, LYRIC antibody, LYRIC/3D3 antibody, metadherin antibody, Metastasis adhesion protein antibody, MTDH antibody, Protein LYRIC antibody
- UniProt ID
- Q86UE4
- 分子量
- 64 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab00189(AEG-1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab00189(AEG-1 antibody) at dilution of 1:200
- 背景介绍
- MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22, the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.
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