产品
本公司产品仅供体外研究使用，不用于临床诊断
AKR1C3 antibody
¥1750
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- AKR1C3 antibody
- 货号
- FNab00262
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
- 别称
- 17 beta HSD 5 antibody, 3 alpha HSD type 2 antibody, 3 alpha HSD type II antibody, brain antibody, AKR1C3 antibody, DD 3 antibody, DD3 antibody, DDX antibody, Dihydrodiol dehydrogenase 3 antibody, HA1753 antibody, HAKRB antibody, HAKRe antibody, hluPGFS antibody, HSD17B5 antibody, Indanol dehydrogenase antibody, KIAA0119 antibody, PGFS antibody, Prostaglandin F synthase antibody
- UniProt ID
- P42330
- 分子量
- 37 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
验证图片
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00262(AKR1C3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat heart using FNab00262(AKR1C3 antibody) at dilution of 1:100
- 背景介绍
- This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.
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