产品
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AKTIP antibody
¥1750
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- AKTIP antibody
- 货号
- FNab00274
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- AKT interacting protein
- 别称
- AKT interacting protein antibody, AKTIP antibody, FT1 antibody, FTS antibody, Fused toes protein homolog antibody
- UniProt ID
- Q9H8T0
- 分子量
- 36 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with FNab00274( AKTIP Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab00274(AKTIP antibody) at dilution of 1:100
- 背景介绍
- The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
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