产品
本公司产品仅供体外研究使用，不用于临床诊断
AMPK gamma 1 antibody
¥1750
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- AMPK gamma 1 antibody
- 货号
- FNab00379
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- protein kinase, AMP-activated, gamma 1 non-catalytic subunit
- 别称
- AMPK gamma1 antibody, AMPK subunit gamma 1 antibody, AMPKG antibody, PRKAG1 antibody
- UniProt ID
- P54619
- 分子量
- 38 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
验证图片
K-562 cells were subjected to SDS PAGE followed by western blot with FNab00379( PRKAG1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab00379( PRKAG1 Antibody) at dilution of 1:50
- 背景介绍
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
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