产品
本公司产品仅供体外研究使用，不用于临床诊断
ANAPC5 antibody
¥1900
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- ANAPC5 antibody
- 货号
- FNab00387
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- anaphase promoting complex subunit 5
- 别称
- ANAPC5 antibody, APC5 antibody, Cyclosome subunit 5 antibody
- UniProt ID
- Q9UJX4
- 分子量
- 85 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab00387(ANAPC5 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab00387(ANAPC5 antibody) at dilution of 1:50
- 背景介绍
- This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
抗体定制服务
抗体定制服务
