产品

本公司产品仅供体外研究使用,不用于临床诊断

Angiopoietin 1 antibody

别称:AGP1 antibody, AGPT antibody, ANG 1 antibody, ANG1 antibody, angiopoietin 1 antibody, ANGPT1 antibody, KIAA0003 antibody
货号:FNab00391反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, WB, IHC
克隆性:polyclonal亚型:IgG
¥1900
规格:
货期: 三个工作日+顺丰快递时长
  • 产品介绍
产品名称
Angiopoietin 1 antibody
货号
FNab00391
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
angiopoietin 1
别称
AGP1 antibody, AGPT antibody, ANG 1 antibody, ANG1 antibody, angiopoietin 1 antibody, ANGPT1 antibody, KIAA0003 antibody
UniProt ID
Q15389
分子量
53 kDa
验证实验
验证实验
ELISA, WB, IHC
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
验证图片
Immunohistochemistry of paraffin-embedded mouse lung using FNab00391(ANGPT1 Antibody) at dilution of 1:100
Immunohistochemistry of paraffin-embedded human esophagus using FNab00391(ANGPT1 Antibody) at dilution of 1:100
背景介绍
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.