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BAD antibody

分类：

研究方向：

说明书 MSDS

¥1750

规格：

货期：三个工作日+顺丰快递时长

产品名称: BAD antibody
货号: FNab00784
规格: 100μg
状态: liquid
纯化方法: Immunogen affinity purified
纯度: ≥95% as determined by SDS-PAGE
克隆性: polyclonal
亚型: IgG
存储: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

免疫原信息

验证实验

验证图片

mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab00784(BAD antibody) at dilution of 1:1000

Immunohistochemistry of paraffin-embedded human prostate hyperplasia tissue slide using FNab00784( BAD Antibody) at dilution of 1:200

Immunofluorescence analysis of HeLa cells using FNab00784( BAD Antibody). Blue: DAPI for nuclear staining.

背景介绍: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.