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BPGM antibody

分类: 研究方向:
别称:DPGM antibody
货号:FNab00934反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, WB, IHC
克隆性:polyclonal亚型:IgG
¥1750
规格:
货期: 三个工作日+顺丰&京东快递时长
  • 产品介绍
产品名称
BPGM antibody
货号
FNab00934
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
2, 3-bisphosphoglycerate mutase
别称
DPGM antibody
UniProt ID
P07738
分子量
30 kDa
验证实验
验证实验
ELISA, WB, IHC
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00934(BPGM antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab00934( BPGM Antibody) at dilution of 1:100
背景介绍
2, 3-diphosphoglycerate (2, 3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2, 3-DPG synthesis via its synthetase activity, and 2, 3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.