产品

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BRAF antibody

别称:BRAF1 antibody, RAFB1 antibody
货号:FNab00941反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, WB, IHC
克隆性:polyclonal亚型:IgG
¥1500
规格:
货期: 三个工作日+顺丰快递时长
  • 产品介绍
产品名称
BRAF antibody
货号
FNab00941
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
v-raf murine sarcoma viral oncogene homolog B1
别称
BRAF1 antibody, RAFB1 antibody
UniProt ID
P15056
分子量
98 kDa
验证实验
验证实验
ELISA, WB, IHC
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00941(BRAF antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human malignant melanoma tissue slide using FNab00941( BRAF Antibody) at dilution of 1:100
背景介绍
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.