mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab03752(HAO antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab03752(HAO1 antibody) at dilution of 1:100
背景介绍
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.