产品

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HARS2 antibody

分类: 研究方向:
别称:HARSL antibody, HARSR antibody, HO3 antibody
货号:FNab03759反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, WB, IHC
克隆性:polyclonal亚型:IgG
¥1750
规格:
货期: 三个工作日+顺丰快递时长
  • 产品介绍
产品名称
HARS2 antibody
货号
FNab03759
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
histidyl-tRNA synthetase 2, mitochondrial (putative)
别称
HARSL antibody, HARSR antibody, HO3 antibody
UniProt ID
P49590
分子量
50 kDa
验证实验
验证实验
ELISA, WB, IHC
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03759(HARS2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab03759(HARS2 antibody) at dilution of 1:100
背景介绍
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.