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HAX1 antibody

分类:
别称:FLJ17042 antibody, FLJ18492 antibody, FLJ93803 antibody, HAX 1 antibody, HAX1 antibody, HCLS1 associated protein X 1 antibody, HCLSBP1 antibody, HS1 associating protein X 1 antibody, HS1 binding protein 1 antibody, HS1BP1 antibody, HSP1BP 1 antibody, SCN3 antibody
货号:FNab03765反应性:Human, Mouse
宿主:Rabbit验证实验:ELISA, WB, IHC, IF
克隆性:polyclonal亚型:IgG
¥1900
规格:
货期: 三个工作日+顺丰快递时长
  • 产品介绍
产品名称
HAX1 antibody
货号
FNab03765
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
HCLS1 associated protein X-1
别称
FLJ17042 antibody, FLJ18492 antibody, FLJ93803 antibody, HAX 1 antibody, HAX1 antibody, HCLS1 associated protein X 1 antibody, HCLSBP1 antibody, HS1 associating protein X 1 antibody, HS1 binding protein 1 antibody, HS1BP1 antibody, HSP1BP 1 antibody, SCN3 antibody
UniProt ID
O00165
分子量
36 kDa
验证实验
验证实验
ELISA, WB, IHC, IF
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
验证图片
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03765( HAX1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart using FNab03765(HAX1 antibody) at dilution of 1:50
Immunofluorescence analysis of A549 cells using FNab03765(HAX1 antibody). Blue: DAPI for nuclear staining.
背景介绍
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.