产品
本公司产品仅供体外研究使用，不用于临床诊断
HDAC1 antibody
¥1500
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- HDAC1 antibody
- 货号
- FNab03792
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- histone deacetylase 1
- 别称
- DKFZp686H12203 antibody, GON 10 antibody, HD1 antibody, HDAC1 antibody, histone deacetylase 1 antibody, RPD3 antibody, RPD3L1 antibody
- UniProt ID
- Q13547
- 分子量
- 60 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:100 - 1:200; IF: 1:50 - 1:100
验证图片
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab03792(HDAC1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03792(HDAC1 antibody) at dilution of 1:100
Immunofluorescence analysis of A549 cells using FNab03792 (HDAC1 antibody). Blue: DAPI for nuclear staining.
- 背景介绍
- Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
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