产品
本公司产品仅供体外研究使用，不用于临床诊断
Histone H2A.X antibody
¥1750
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- Histone H2A.X antibody
- 货号
- FNab03885
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- H2A histone family, member X
- 别称
- H2A histone family antibody, member X antibody, H2A.X antibody, H2A/X antibody, H2AFX antibody, H2AX antibody, Histone H2A.x antibody
- UniProt ID
- P16104
- 分子量
- 16 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:100 - 1:200; IF: 1:50 - 1:200
验证图片
HL-60 cells were subjected to SDS PAGE followed by western blot with FNab03885(H2AFX antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab03885(H2AFX antibody) at dilution of 1:100
- 背景介绍
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
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