产品
本公司产品仅供体外研究使用，不用于临床诊断
TBCD antibody
¥1900
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- TBCD antibody
- 货号
- FNab08519
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- tubulin folding cofactor D
- 别称
- KIAA0988 antibody, SSD1 antibody, TFCD antibody
- UniProt ID
- Q9BTW9
- 分子量
- 130 kDa
验证实验
- 验证实验
- ELISA, WB, IP
- 建议稀释比例
- WB: 1:500-1:2000; IP: 1:200-1:2000
验证图片
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08519(TBCD antibody) at dilution of 1:500
IP Result of anti-TBCD (IP:FNab08519, 4ug; Detection:FNab08519 1:500) with mouse brain tissue lysate 3440ug.
- 背景介绍
- Tubulin-folding protein; involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin(TUBB). Acts as a GTPase-activating protein(GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.
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