产品
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TEX14 antibody
¥1900
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- TEX14 antibody
- 货号
- FNab08609
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- testis expressed 14
- 别称
- SGK307 antibody
- UniProt ID
- Q8IWB6
- 分子量
- 180-200 kDa, 106 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IP
- 建议稀释比例
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
验证图片
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08609(TEX14 antibody) at dilution of 1:500
IP Result of anti-TEX14 (IP:FNab08609, 4ug; Detection:FNab08609 1:500) with mouse testis tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human testis using FNab08609(TEX14 antibody) at dilution of 1:50
- 背景介绍
- Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro(By similarity).
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