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Transferrin antibody

分类: 研究方向:
别称:Beta 1 metal binding globulin antibody, DKFZp781D0156 antibody, PRO1557 antibody, PRO2086 antibody, Serotransferrin antibody, Siderophilin antibody, TF antibody, Transferrin antibody
货号:FNab08930反应性:Human
宿主:Mouse验证实验:ELISA, WB, IHC
克隆性:monoclonal亚型:IgG1
¥2100
规格:
货期: 三个工作日+顺丰&京东快递时长
  • 产品介绍
产品名称
Transferrin antibody
货号
FNab08930
规格
100μg
状态
liquid
纯化方法
Protein A+G purification
纯度
≥95% as determined by SDS-PAGE
克隆性
monoclonal
亚型
IgG1
Clone ID
6G10
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
transferrin
别称
Beta 1 metal binding globulin antibody, DKFZp781D0156 antibody, PRO1557 antibody, PRO2086 antibody, Serotransferrin antibody, Siderophilin antibody, TF antibody, Transferrin antibody
UniProt ID
P02787
分子量
77 kDa
验证实验
验证实验
ELISA, WB, IHC
建议稀释比例
WB: 1:2000-1:20000; IHC: 1:20-1:200
验证图片
human plasma tissue were diluted two fold and subjected to SDS PAGE followed by western blot with FNab08930(TF Antibody) at dilution of 1:16000
Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab08930(TF Antibody) at dilution of 1:50
背景介绍
Serotransferrin(TF) is a 77 kDa secreted protein which is also named as transferrin, siderophilin, beta-1 metal-binding globulin and belongs to a family of homologous iron-binding glycoproteins that encompasses lactoferrin(found both intracellular and in secretions, including milk), melanotrasferrin(present on melanoma cells) and ovotransferrin(present in egg white). TF is a multi-function protein with a primary role in transporting iron in a safe, redox-inactive state from absorption to utilization or storage sites around the body. The association of Tf with the immune system derives from its ability to restrict serum free-iron levels, creating low-iron environments where the infection capacity of pathogenic microorganisms is limited. TF is expressed predominantly in the liver and secreted in plasma, but lower amounts can be synthesized in other tissues such as the brain and the testis