产品

本公司产品仅供体外研究使用,不用于临床诊断

USP14 antibody

分类: 研究方向:
别称:Deubiquitinating enzyme 14 antibody, TGT antibody, Ubiquitin thiolesterase 14 antibody, USP14 antibody
货号:FNab09310反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, WB, IF, FC
克隆性:polyclonal亚型:IgG
¥1900
规格:
货期: 三个工作日+顺丰&京东快递时长
  • 产品介绍
产品名称
USP14 antibody
货号
FNab09310
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
ubiquitin specific peptidase 14(tRNA-guanine transglycosylase)
别称
Deubiquitinating enzyme 14 antibody, TGT antibody, Ubiquitin thiolesterase 14 antibody, USP14 antibody
UniProt ID
P54578
分子量
52-60 kDa
验证实验
验证实验
ELISA, WB, IF, FC
建议稀释比例
WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100
验证图片
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab09310(USP14 antibody) at dilution of 1:300
背景介绍
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation(ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions(NMJs).