产品
本公司产品仅供体外研究使用，不用于临床诊断
USP16 antibody
¥1900
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- USP16 antibody
- 货号
- FNab09312
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- ubiquitin specific peptidase 16
- 别称
- Deubiquitinating enzyme 16 antibody, Ubiquitin thiolesterase 16 antibody, UBP M antibody, USP16 antibody
- UniProt ID
- Q9Y5T5
- 分子量
- 94 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IP
- 建议稀释比例
- WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200
验证图片
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09312(USP16 antibody) at dilution of 1:1000
IP Result of anti-USP16 (IP:FNab09312, 5ug; Detection:FNab09312 1:1000) with HeLa cells lysate 880ug.
Immunohistochemistry of paraffin-embedded human kidney using FNab09312(USP16 antibody) at dilution of 1:100
- 背景介绍
- Specifically deubiquitinates 'Lys-120' of histone H2A(H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3(H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B-and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
抗体定制服务
抗体定制服务
