产品
本公司产品仅供体外研究使用，不用于临床诊断
USP21 antibody
¥2100
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- USP21 antibody
- 货号
- FNab09318
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- ubiquitin specific peptidase 21
- 别称
- Deubiquitinating enzyme 21 antibody, Ubiquitin thiolesterase 21 antibody, USP16 antibody, USP21 antibody, USP23 antibody
- UniProt ID
- Q9UK80
- 分子量
- 63 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:200-1:2000; IHC: 1:20-1:200
验证图片
RAW 264.7 cells were subjected to SDS PAGE followed by western blot with FNab09318(USP21 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab09318(USP21 Antibody) at dilution of 1:50
- 背景介绍
- Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di-and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination(By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates(PubMed:10799498). Deubiquitinates BAZ2A/TIP5 leading to its stabilization(PubMed:26100909).
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