产品
本公司产品仅供体外研究使用，不用于临床诊断
USP37 antibody
¥1900
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- USP37 antibody
- 货号
- FNab09330
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- ubiquitin specific peptidase 37
- 别称
- Deubiquitinating enzyme 37 antibody, KIAA1594 antibody, Ubiquitin thiolesterase 37 antibody, USP37 antibody
- UniProt ID
- Q86T82
- 分子量
- 110 kDa,70 kDa
验证实验
- 验证实验
- ELISA, WB
- 建议稀释比例
- WB: 1:500-1:5000; IP: 1：200-1：2000
验证图片
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09330(USP37 antibody) at dilution of 1:500
- 背景介绍
- Deubiquitinase that antagonizes the anaphase-promoting complex(APC/C) during G1/S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2).
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