产品
本公司产品仅供体外研究使用，不用于临床诊断
USP44 antibody
¥2100
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- USP44 antibody
- 货号
- FNab09334
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- ubiquitin specific peptidase 44
- 别称
- Deubiquitinating enzyme 44 antibody, DKFZp434D0127 antibody, FLJ14528 antibody, Ubiquitin thiolesterase 44 antibody, USP44 antibody
- UniProt ID
- Q9H0E7
- 分子量
- 81 kDa
验证实验
- 验证实验
- ELISA, WB
- 建议稀释比例
- WB: 1:500-1:5000
验证图片
human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09334(USP44 antibody) at dilution of 1:500
- 背景介绍
- Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome(APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex(also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B(H2BK120ub1) ubiquitination.
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