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VHL antibody

分类：

研究方向：

别称：	HRCA1 antibody, Protein G7 antibody, pVHL antibody, RCA1 antibody, VHL antibody, VHL1 antibody, Von Hippe-Lindau antibody
货号：	FNab09402	反应性：	Human, Mouse, Rat
宿主：	Rabbit	验证实验：	ELISA, WB, IHC, IF
克隆性：	polyclonal	亚型：	IgG

说明书

¥1500

规格：

货期：三个工作日+顺丰&京东快递时长

产品名称: VHL antibody
货号: FNab09402
规格: 100μg
状态: liquid
纯化方法: Immunogen affinity purified
纯度: ≥95% as determined by SDS-PAGE
克隆性: polyclonal
亚型: IgG
存储: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

免疫原信息

免疫原: von Hippel-Lindau tumor suppressor
别称: HRCA1 antibody, Protein G7 antibody, pVHL antibody, RCA1 antibody, VHL antibody, VHL1 antibody, Von Hippe-Lindau antibody
UniProt ID: P40337
分子量: 18-24 kDa

验证实验

验证图片

293T cells were subjected to SDS PAGE followed by western blot with FNab09402(VHL antibody) at dilution of 1:1000

Immunohistochemical of paraffin-embedded human kidney using FNab09402(VHL antibody) at dilution of 1:50?

背景介绍: Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor(HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2.