产品
本公司产品仅供体外研究使用，不用于临床诊断
Villin antibody
¥1900
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- Villin antibody
- 货号
- FNab09406
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- villin 1
- 别称
- VIL antibody, VIL1 antibody, Villin antibody, villin 1 antibody
- UniProt ID
- P09327
- 分子量
- 93 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:1000-1:10000; IHC: 1:50-1:8000; IF: 1:20-1:200; IP: 1:200-1:1000
验证图片
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab09406(VIL1 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab09406(VIL1 Antibody) at dilution of 1:200
- 背景介绍
- Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
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